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Also available in 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator. purity: 99%
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
LRH-1 modulator-1 is a research-grade small molecule characterized as a potent agonist/modulator of the liver receptor homolog-1 (LRH-1). The product is provided with analytical documentation and recommended storage and solubility guidance for laboratory and preclinical use.
Potent LRH-1 modulator/agonist for receptor biology studies.
High purity (98.0%) suitable for analytical and biological assays.
Supplied with certificate of analysis, HNMR, and LCMS data for verification.
Soluble in DMSO; in vivo formulation protocols are provided.
Stable under specified storage conditions with solvent-specific guidelines.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
TUG-770 (CAS 1402601-82-4) is a potent agonist of the free fatty acid receptor 1 (FFA1/GPR40) a G protein-coupled receptor implicated in the enhancement of glucose-stimulated insulin secretion by pancreatic -cells TUG-770 demonstrates high affinity for FFA1 with an EC50 of 6 nM and over 150-fold selectivity compared to FFA4 as well as high selectivity over other receptors and transporters In INS-1E rat -cell lines TUG-770 promotes insulin secretion in the presence of elevated glucose Pharmacokinetic studies in mice indicate favorable oral absorption and bioavailability with dose-dependent reductions in blood glucose during glucose tolerance tests TUG-770 is a valuable tool for investigating FFA1-mediated pathways and glucose homeostasis in metabolic research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More